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Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow

13 Dec 2018

Abstract excerpt

Long noncoding RNAs (lncRNAs) are regulators of cell differentiation and development. The lncRNA transcriptome in human hematopoietic stem and progenitor cells is not comprehensively defined. We investigated lncRNAs in 979 human bone marrow-derived CD34+ cells by single cell RNA sequencing followed by de novo transcriptome reconstruction. We identified 3,173 lncRNAs in total, among which 2,365 were previously...

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Cancer-related molecular mechanisms research
Mycobacterium research and diagnosis
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30545929
DOI: 10.3324/haematol.2018.208926

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