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Bactericidal activity of ZnO nanoparticles-anti TB drugs combination towards H37Rv strain and multidrug-resistant isolates of <i>Mycobacterium tuberculosis</i> via SufB splicing inhibition

2025-03-14

Abstract excerpt

Tuberculosis (TB) remains a significant global health threat, claiming millions of lives annually. Despite advancements in treatment, the emergence of drug-resistant strains has hindered effective TB control. The current management for TB is prolonged with severe side effects, leading to poor patient compliance. Metal-based nanoparticles are shown to manage drug-sensitive TB when combined with anti-TB drugs. Howev...

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Literature Corpus work
a6c35bea-9993-50d9-806a-e0f41ccd05f4
DOI
10.1101/2025.03.13.643114
Open publication

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