Article

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

2023-05-30

Abstract excerpt

<title>Abstract</title> <p>More than 10 million people suffer from lung diseases caused by the pathogenic fungus <italic>Aspergillus fumigatus</italic>. The azole class of antifungals represent first line therapeutics for most of these infections however resistance is rising. Identification of novel antifungal targets that, when inhibited, synergise with the azoles will aid the development of agents that can impr...

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Literature Corpus work: a6b63191-bdff-546e-b0d7-32138fcc2e5d
DOI: 10.21203/rs.3.rs-2960526/v1

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