Aminoethylated chitooligomers and their apoptotic activity on AGS human cancer cells

Abstract excerpt

In this study, the ability of aminoethylation of chitooligomers (COS) to inhibit the proliferation of AGS human gastric adenocarcinoma cells was evaluated using COS with lower molecular weight (<1kDa). As water-soluble aminoderivatized COS derivatives, aminoethyl-COS (AE-COS), dimethyl aminoethyl-COS (DMAE-COS) and diethyl aminoethyl-COS (DEAE-COS) were synthesized and confirmed by their IR spectra results in comp...

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• Cancer Mechanisms and Therapy
• Cytokine Signaling Pathways and Interactions
• Free Radicals and Antioxidants
• Fungal Plant Pathogen Control
• Ion Channels and Receptors
• Medicinal Plants and Neuroprotection
• Metal complexes synthesis and properties
• Protein Tyrosine Phosphatases

Identifiers and source

Literature Corpus work

a6022a33-2359-5ea3-87d0-4fc630332ad0

DOI

10.1016/j.carbpol.2011.09.034