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In silico and in vitro investigation of anticancer effect of newly synthesized nonivamide-s-allyl cysteine ester

3 Aug 2021

Abstract excerpt

Nonivamide (NOV), less pungent analogue of capsaicin present in various Capsicum species is known for various biological properties. S-allyl cysteine (SAC) abundantly present in aged garlic extract is gaining importance for anticancer property. NOV was esterified with SAC to increase the biological activity. In silico ADME analysis revealed the drug-likeness of NOV-SAC. Molecular docking and dynamics simulation...

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PMID: 34344261
DOI: 10.1080/07391102.2021.1959404

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