Article

Chitooligomers inhibit UV-A-induced photoaging of skin by regulating TGF-β/Smad signaling cascade

2012-04-01

Abstract excerpt

In the present study, effect of low molecular weight chitooligomers on prevention of photoaging in UV-A irradiated in vitro human dermal fibroblasts was investigated. The results indicated that chitooligomers suppressed family of collagenase (MMP-1, MMP-8 and MMP-13) and gelatinase (MMP-2 and MMP-9) MMPs expression. These levels were inhibited by increase in expression of TIMP-1 and TIMP-2 genes. In addition, trea...

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Identifiers and source

Literature Corpus work: 058221c3-321a-5a18-aa78-a3440f1986af
DOI: 10.1016/j.carbpol.2011.12.032

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