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Culture-independent identification and serotyping of <i>Streptococcus pneumoniae</i> by targeted metagenomics in pleural fluid samples

2026-04-16

Abstract excerpt

2. Streptococcus pneumoniae is the leading cause of empyema and pneumonia in children, and monitoring of effectiveness of polyvalent pneumococcal vaccines has been essential for controlling invasive pneumococcal disease (IPD) in children and elderly adults. Conventional serotyping of pneumococci has relied on Quellung reaction following laboratory culture, however more recently whole genome sequencing (WGS) has be...

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Literature Corpus work
7a449318-9ec7-5e7a-8d9e-1403c2c32045
DOI
10.64898/2026.04.13.26350812
Open publication

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Culture-independent identification and serotyping of <i>Streptococcus pneumoniae</i> by targeted metagenomics in pleural fluid samplesDOI 10.64898/2026.04.13.26350812
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