Article

Integration of Donor Microbiota Following FMT Predicts Anti–PD-1 Response in Melanoma

2025-09-05

Abstract excerpt

<title>Abstract</title> <p>Fecal microbiota transplantation (FMT) has shown promise improving anti–PD-1 therapy in melanoma, but the underlying microbial features remain poorly defined. We performed strain-resolved metagenomic analysis of three clinical trials and found therapeutic benefit was linked to successful integration of donor microbiota, rather than increased diversity or engraftment of specific species....

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Literature Corpus work: a59559d4-97d0-5392-bc86-2e7398028079
DOI: 10.21203/rs.3.rs-7483676/v1

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