Article

Juvenile Idiopathic Arthritis Fibroblast-like Synoviocytes, through BMP signaling, play a central role in joint growth disturbances

2020-02-05

Abstract excerpt

<title>Abstract</title> <p>Background: To examine critical interactions between juvenile idiopathic arthritis synovial fibroblasts (JFLS) and chondrocytes (Ch), and their role in bony overgrowth seen in patients with juvenile idiopathic arthritis (JIA). <h4>Methods:</h4> Control (CFLS) and JFLS were cultured in media containing recombinant BMP4. Ch were cultured in either CFLS or JFLS conditioned-media. Media sup...

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Literature Corpus work: a4fe00e1-4942-55b4-9c22-7617fa417903
DOI: 10.21203/rs.2.22272/v1

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