Article
The pathophysiology of the growth plate in juvenile idiopathic arthritis
7 Sept 2005
Abstract excerpt
Children with chronic inflammatory diseases, such as juvenile idiopathic arthritis (JIA), suffer from a variety of growth disorders. These range from general growth retardation to local acceleration of growth in the affected limb. These disorders are associated with the increased production of proinflammatory cytokines, which may influence growth through a local effect in the growth plates of long bones and/or...
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