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Article

LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesis

5 Dec 2019

Abstract excerpt

Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BC) with the most aggressive phenotype and poor overall survival. Using bioinformatics tools, we identified LINC00908 encoding a 60-aa polypeptide and differentially expressed in TNBC tissues. We named this endogenously expressed polypeptide ASRPS (a small regulatory peptide of STAT3). ASRPS expression was down-regulated in TNBCs and associated...

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PMID: 31816634
DOI: 10.1084/jem.20190950

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