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Article

Role of Plasmatic and Urinary Concentration of Tenofovir Disoproxil Fumarate in a Cohort of Patients Affected by Chronic Hepatitis B

2021-06-17

Abstract excerpt

<title>Abstract</title> <p>The aim of this study was the evaluation of plasmatic and urinary therapeutic drug monitoring (TDM) of tenofovir disoproxil fumarate (TDF) in a cohort of patients affected by chronic hepatitis B (CHB). In 68 enrolled patients eGFR was 68 ml/min in naive, while in adefovir dipivoxil (ADV) pretreated patients was 55.5 ml/min (<italic>p</italic><0.001). The HBV E genotype was related to lo...

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Literature Corpus work
a4979367-81b4-503a-93f2-258e58ff7b75
DOI
10.21203/rs.3.rs-592142/v1
Open publication

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