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Tenofovir alafenamide clinical pharmacology

10 Dec 2021

Abstract excerpt

Tenofovir today exists in two pharmaceutical forms, such as Tenofovir disoproxil fumarate (TDF) and the newer Tenofovir alafenamide (TAF). The two different salts are required in order to promote intestinal absorption of the active molecule (TFV). Once absorbed the distribution of TFV into compartments is driven by the salt to which the drug is conjugated; in case of TDF, following absorption most of TFV is...

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PMID: 35146360
DOI: 10.53854/liim-2904-4

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