Article

Chronic gut inflammation impairs contextual control of fear

2022-08-17

Abstract excerpt

Chronic inflammatory diseases are highly comorbid with anxiety in humans. The extent to which chronic inflammation is responsible for this relationship remains to be determined. We therefore tested the hypothesis that prolonged, but not brief, gut inflammation is sufficient to evoke anxiety-related behaviours in mice. We used the discriminative fear to context conditioning paradigm to assess fear generalization, w...

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Literature Corpus work: a49423b6-778b-57e7-ab78-990f7face059
DOI: 10.21203/rs.3.rs-1898972/v1

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