Article

Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinoma

2022-08-19

Abstract excerpt

<h4>Background: </h4> Today, individual prognosis in patients with adenocarcinoma of the esophagus (EAC) is based on post-surgical TNM staging and valid biomarkers are still not implemented. Integrin beta1 (ITGB1) is widely expressed in epithelial cells and promotes cell adhesion and growth. Its impact on tumor progression was described for different tumor entities before, data on its function as biomarker in EAC...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a486c452-4b1f-5ed2-b011-990c73373da2
DOI: 10.21203/rs.3.rs-1934344/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinomaDOI 10.21203/rs.3.rs-1934344/v1Read

A Bioinformatic Investigation into the Role of ITGB1 in Cancer Prognosis and Therapeutic ResistanceSemantic proximity Read

ITGB1 as a prognostic biomarker correlated with immune suppression in gastric cancerSemantic proximity Read

A Comprehensive Analysis of Potential Gastric Cancer Prognostic Biomarker ITGBL1 Associated With Immune Infiltration and Epithelial–mesenchymal TransitionSemantic proximity Read

Comprehensive Analysis of the Prognostic Value of ITGB Superfamily Members in Gastric Cancer Using Bioinformatics AnalysisSemantic proximity Read

ITGBL1 Predicts a Poor Prognosis and Correlates EMT Phenotype in Gastric CancerSemantic proximity Read

Integrin-based prognostic model predicts survival, immunotherapy response, and drug sensitivity in gastric cancerSemantic proximity Read

Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancerSemantic proximity Read

A Pan-Cancer Analysis of the Oncogenic Role of Integrin Beta4 (ITGB4) in Human TumorsSemantic proximity Read

ITGA5 is a prognostic biomarker and correlated with immune infiltration in gastrointestinal tumorsSemantic proximity Read

Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targetsSemantic proximity Read

Integrins Within the Tumor Microenvironment: Biological Functions and Advances in Therapeutic Targeting <strong> </strong>Semantic proximity Read

Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancerSemantic proximity Read