Article

Transcriptomic profiling of plaque psoriasis and cutaneous T cell subsets during treatment with secukinumab

2019-09-10

Abstract excerpt

The IL17A inhibitor secukinumab is efficacious for the treatment of psoriasis. In order to define its mechanism of action, it is important to understand its impact on psoriatic whole skin tissue as well as specific skin-resident immune cell populations such as T lymphocytes. In this study, we treated 15 moderate-to-severe plaque psoriasis patients with secukinumab and characterized the longitudinal transcriptomic...

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Literature Corpus work: a447d13f-1102-56b3-a5b3-1f42851ecd57
DOI: 10.1101/764118

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