Article

TaxiBGC: a Taxonomy-guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes

2021-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Biosynthetic gene clusters (BGCs) in microbial genomes encode for bioactive secondary metabolites (SMs), which can play important roles in microbe-microbe and host-microbe interactions. Given the biological significance of SMs and the current profound interest in the metabolic functions of microbiomes, the unbiased identification of BGCs from high-throughput metagenomic data could offer novel in...

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Literature Corpus work: a4335f47-356f-5498-8093-1e7e244eccf6
DOI: 10.1101/2021.07.30.454505

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