Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence modeling tools to decode the biosynthetic diversity of the human microbiome

30 Jun 2025

Abstract excerpt

Understanding the biosynthetic potential of the human microbiome remains a significant challenge with far-reaching scientific and translational implications. Analyses of human-associated (meta)genomic sequencing data undeniably show that the biosynthetic diversity encoded in these genomes is largely underexplored. A crucial step in studying specialized metabolites involves the sequence-based identification of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to Microbial Metabolic Engineering and Bioproduction
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40586419
DOI: 10.1128/msystems.00333-25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence modeling tools to decode the biosynthetic diversity of the human microbiomePMID 40586419Read ↗

ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human MicrobiomeSemantic proximity Read ↗

ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human MicrobiomeSemantic proximity Read ↗

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of AntibioticsSemantic proximity Read ↗

A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sitesSemantic proximity Read ↗

GutCyc: a Multi-Study Collection of Human Gut Microbiome Metabolic ModelsSemantic proximity Read ↗

Functional Anabolic Network Analysis of Human-associated <i>Lactobacillus</i> StrainsSemantic proximity Read ↗

A human gut metagenome-assembled genome catalogue spanning 41 countries supports genome-scale metabolic modelsSemantic proximity Read ↗

A new genomic blueprint of the human gut microbiotaSemantic proximity Read ↗

From next-generation sequencing to systematic modeling of the gut microbiomeSemantic proximity Read ↗

CarveMe-GutMicrobes: Automated Metabolic Model Reconstruction for Gut Microbial Species and CommunitiesSemantic proximity Read ↗

A systematic analysis of metabolic pathways in the human gut microbiotaSemantic proximity Read ↗

Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.