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Autism excitation-inhibition imbalance linked to brain hyperconnectivity: An analysis based on 657 autistic subjects

2022-07-16

Abstract excerpt

The large heterogeneity in autism spectrum disorder (ASD) is a major drawback for the development of therapies. Here, we apply consensus-subtyping strategies based on functional connectivity patterns to a population of N=657 quality-assured autistic subjects. We found two major subtypes (each divided hierarchically into several minor subtypes): Subtype 1 exhibited hypoconnectivity (less average connectivity than t...

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Identifiers and source

Literature Corpus work
af892d27-3cf5-5867-9562-6a138dcb7c05
DOI
10.1101/2022.07.14.500131
Open publication

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Autism excitation-inhibition imbalance linked to brain hyperconnectivity: An analysis based on 657 autistic subjectsDOI 10.1101/2022.07.14.500131
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