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Article

Sirtuin1 deficiency could exacerbate melanocyte apoptosis under endoplasmic reticulum stress

2024-11-11

Abstract excerpt

<title>Abstract</title> <p>Vitiligo is a depigmentation disease caused by the targeted destruction of melanocytes, resulting in skin and hair depigmentation and significant psychological stress. However, the mechanisms underlying its onset and progression remain unclear. Endoplasmic reticulum (ER) stress, linked with oxidative stress and autoimmunity, is involved in the development of vitiligo, and prolonged ER s...

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Literature Corpus work
a3a26667-6ee2-5152-9bd1-fa3304f1ac26
DOI
10.21203/rs.3.rs-5360560/v1
Open publication

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