Article

18F-APN-1607 Tau PET in Progressive Supranuclear Palsy-Like Symptoms Caused by TBK1 Mutations

2021-11-08

Abstract excerpt

<title>Abstract</title> <p>Background Pathogenic mutations in the TANK-binding kinase 1 (<italic>TBK1</italic>) gene have been associated with progressive supranuclear palsy (PSP)-like extrapyramidal symptoms, amyotrophic lateral sclerosis (ALS), as well as cognitive and behavioral alterations. However, the question as to whether <italic>TBK1</italic> mutations may be associated with tau burden remains unanswere...

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Literature Corpus work: a39c27c7-5165-50f2-998b-5bdaf0205b55
DOI: 10.21203/rs.3.rs-1031231/v1

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