Article
In Vivo 18 F-APN-1607 Tau Positron Emission Tomography Imaging in MAPT Mutations: Cross-Sectional and Longitudinal Findings.
Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2022
Zhou Xin-Yue, Lu Jia-Ying, Liu Feng-Tao, Wu Ping, Zhao Jue, Ju Zi-Zhao, Tang Yi-Lin, Shi Qing-Yi, Lin Hua-Mei, Wu Jian-Jun, Yen Tzu-Chen, Zuo Chuan-Tao, Sun Yi-Min, Wang Jian
Abstract excerpt
BACKGROUND: Frontotemporal lobar degeneration with tauopathy caused by MAPT (microtubule-associated protein tau) mutations is a highly heterogenous disorder. The ability to visualize and longitudinally monitor tau deposits may be beneficial to understand disease pathophysiology and predict clinical trajectories. OBJECTIVE: The aim of this study was to investigate the cross-sectional and longitudinal 18 F-APN-1607...
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