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Application of Elevated Atmospheric Pressure and Hypoxia Enhance Pluripotency and Stem Cell Differentiation

2024-01-22

Abstract excerpt

<h4>Summary</h4> Physical forces regulate stem cell differentiation in-vivo, however few simple and precise methods exist to better understand this biology in-vitro. Here we describe the use of a novel bioreactor that enables addition of physical force in the form of elevated atmospheric pressure during reprogramming of human fibroblasts and culture of human induced pluripotent stem cell (iPSC) and neural stem ce...

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Literature Corpus work
a344239d-6a5f-5caa-af3d-83dcf0f93d67
DOI
10.1101/2024.01.19.576329
Open publication

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Application of Elevated Atmospheric Pressure and Hypoxia Enhance Pluripotency and Stem Cell DifferentiationDOI 10.1101/2024.01.19.576329
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