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Article

A Self-Sustaining Mechanism for Endothelial Tension Maintenance Through GqGPCR Signaling

2026-04-26

Abstract excerpt

The vascular endothelium maintains homeostasis by acting as a selective barrier, permitting the exchange of nutrients, immune cells, and signaling molecules while restricting pathogens. It further regulates vascular function by generating and sustaining mechanical tension. Aging and disease alter the vascular environment and disrupt the regulation of endothelial tension, contributing to vascular diseases such as h...

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Literature Corpus work
a3134d2e-74b6-581a-84bc-e3f280220012
DOI
10.64898/2026.04.22.720219
Open publication

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A Self-Sustaining Mechanism for Endothelial Tension Maintenance Through GqGPCR SignalingDOI 10.64898/2026.04.22.720219
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