Article

Average genome size estimation enables accurate quantification of gene family abundance and sheds light on the functional ecology of the human microbiome

2014-09-11

Abstract excerpt

Average genome size (AGS) is an important, yet often overlooked property of microbial communities. We developed MicrobeCensus to rapidly and accurately estimate AGS from short-read metagenomics data and applied our tool to over 1,300 human microbiome samples. We found that AGS differs significantly within and between body sites and tracks with major functional and taxonomic differences. For example, in the gut, AG...

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Literature Corpus work: a2b53d83-d5a8-55c9-9f25-ae2df4dcd5f2
DOI: 10.1101/009001

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