Article

Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes

2020-02-14

Abstract excerpt

<title>Abstract</title> <p>Background Shotgun metagenomes are often assembled prior to annotation of genes which biases the functional capacity of a community towards its most abundant members. For an unbiased assessment of community function, short reads need to be mapped directly to a gene or protein database. The ability to detect genes in short read sequences is dependent on pre- and post-sequencing decisions...

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Literature Corpus work: fde8a933-baa3-5b24-a256-66f420a4c912
DOI: 10.21203/rs.2.16066/v3

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