Article

Breast cancer epigenetics: comprehensive investigation of genes and chemical compounds involved in active DNA demethylation

2023-04-12

Abstract excerpt

<h4>Background: </h4> The experimental evidence has demonstrated that active DNA demethylation process, which involves TET proteins, can affect DNA methylation pattern. TET dependent demethylation residues in DNA hypomethylation by oxidation 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) and its derivatives. TETs’ activity may be upregulated by ascorbate. Given that aberrant DNA methylation of crucial...

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Literature Corpus work: a2902e80-a33d-59d1-93f8-e0c3095e4fba
DOI: 10.21203/rs.3.rs-2778971/v1

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