Article

Evasion of Neutralizing Antibody Response by the SARS-CoC-2 BA.2.75 Variant

2022-08-16

Abstract excerpt

The newly emerged BA.2.75 SARS-CoV-2 variant exhibits an alarming 9 additional mutations in its spike (S) protein compared to the ancestral BA.2 variant. Here we examine the neutralizing antibody escape of BA.2.75 in mRNA-vaccinated and BA.1-infected individuals, as well as the molecular basis underlying functional changes in the S protein. Notably, BA.2.75 exhibits enhanced neutralization resistance over BA.2, bu...

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Literature Corpus work: a25f3dda-fdb9-5321-8356-60c922be5cfe
DOI: 10.2139/ssrn.4191910

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