Article
Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike.
Nature - 1 Dec 2023
Wang Qian, Guo Yicheng, Liu Liyuan, Schwanz Logan T, Li Zhiteng, Nair Manoj S, Ho Jerren, Zhang Richard M, Iketani Sho, Yu Jian, Huang Yiming, Qu Yiming, Valdez Riccardo, Lauring Adam S, Huang Yaoxing, Gordon Aubree, Wang Harris H, Liu Lihong, Ho David D
Abstract excerpt
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.2.86, has emerged and spread to numerous countries worldwide, raising alarm because its spike protein contains 34 additional mutations compared with its BA.2 predecessor1. We examined its antigenicity using human sera and monoclonal antibodies (mAbs). Reassuringly, BA.2.86 was no more resistant to human sera than the currently...
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