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How and why multicopy genes survive on the human Y chromosome

2024-04-03

Abstract excerpt

The mammalian Y chromosome is an evolutionary paradox: it cannot recombine across most of its length and has lost many genes, yet it retains multicopy gene families required for sperm production. How these genes survive has been difficult to resolve because their near-identical copies collapse in most genome assemblies and are difficult to analyze accurately with short RNA reads. Using telomere-to-telomere assembl...

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Literature Corpus work
a25caf35-2c06-53c2-b55e-040479fe05cb
DOI
10.1101/2024.04.02.587783
Open publication

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How and why multicopy genes survive on the human Y chromosomeDOI 10.1101/2024.04.02.587783
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