Article

Extracellular vesicles containing anti-miR-128-3p derived from mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by suppressing neuronal pyroptosis and modulating microglia polarization

2024-02-21

Abstract excerpt

Cerebral ischemia-reperfusion (CI/R) injury seriously threatens the patients with ischemic stroke. MiR-128-3p level was found to be upregulated in serum samples of patients with ischemic stroke. It has been shown that miRNA in extracellular vesicles (specifically exosomes) has attracted attention because mesenchymal stem cells (MSCs)-derived exosomes play a favorable role in improving CI/R injury. Thus, we investi...

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Literature Corpus work: 2f1de17d-7176-521a-bae2-d6d40751cbbc
DOI: 10.21203/rs.3.rs-3964083/v1

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