Article

Machine-learning annotation of human splicing branchpoints

2016-12-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The branchpoint element is required for the first lariat-forming reaction in splicing. However due to difficulty in experimentally mapping at a genome-wide scale, current catalogues are incomplete. <h4>Results</h4> We have developed a machine-learning algorithm trained with empirical human branchpoint annotations to identify branchpoint elements from primary genome sequence...

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Literature Corpus work: a1e2deca-cc3d-54f6-94d2-ba688b27d94c
DOI: 10.1101/094003

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