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Article

Machine learning annotation of human branchpoints.

Bioinformatics (Oxford, England) - 15 Mar 2018

Signal Bethany, Gloss Brian S, Dinger Marcel E, Mercer Tim R

Abstract excerpt

Motivation: The branchpoint element is required for the first lariat-forming reaction in splicing. However current catalogues of human branchpoints remain incomplete due to the difficulty in experimentally identifying these splicing elements. To address this limitation, we have developed a machine-learning algorithm-branchpointer-to identify branchpoint elements solely from gene annotations and genomic sequence....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29092009
DOI: 10.1093/bioinformatics/btx688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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