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Multi-Trait Genetic Association Reveal a Central Mechanism in the Comorbidity of Hyperuricemia and Hyperlipidemia

2025-12-09

Abstract excerpt

<h4>Background: </h4> Hyperuricemia and hyperlipidemia frequently coexist in metabolic syndrome, yet their shared pathogenic mechanisms remain insufficiently elucidated. Identifying convergent molecular pathways may provide novel therapeutic targets for metabolic comorbidity. <h4>Methods:</h4> A multi-omics strategy integrating multi-trait genome-wide association analysis (MTAG), weighted gene co-expression networ...

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Literature Corpus work
a171021a-f5a4-5cf7-805a-9473170de744
DOI
10.20944/preprints202512.0761.v1
Open publication

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