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Atg1 modulates mitochondrial dynamics to promote germline stem cell maintenance in <i>Drosophila</i>

2022-09-08

Abstract excerpt

Mitochondrial dynamics (fusion and fission) are necessary for stem cell maintenance and differentiation. However, the relationship between mitophagy, mitochondrial dynamics and stem cell exhaustion is not clearly understood. Here we report the multifaceted role of Atg1 in mitophagy, mitochondrial dynamics and stem cell maintenance in female germline stem cells (GSCs) in Drosophila . We found that depletion of At...

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Literature Corpus work
a1514b26-9ed7-565f-be04-701273dc57c6
DOI
10.1101/2022.09.08.507105
Open publication

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