Article

New Natural Compound Inhibitors of Checkpoint Kinase-1(CHK1) Based on Computational Study

2021-05-17

Abstract excerpt

As a malignant tumor of the ovary, the general treatment principle of ovarian cancer is surgical treatment, supplemented by chemotherapy, and some patients can use targeted drugs. Its treatment effect is relatively poor, so the prognosis is poor, the mortality rate is high. To contribute to drug design and refinement, ideal lead compounds with potential inhibitory effects on ATP-competitive CHK1 (Checkpoint kinase...

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Literature Corpus work: a1029c33-51cd-5674-b446-d2a4b60693f9
DOI: 10.21203/rs.3.rs-509168/v1

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