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Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C.

Anti-cancer drugs - 1 Jun 2023

Yang Wenzhuo, Ge Junliang, Yuan Meng, Li Jialin, Pan Lin, Ren Junan, Dou Gaojing, Yang Laiyu, Zhou Yang, Xie Haoqun, Wang Xinhui, Hu Hongrong

Abstract excerpt

Lung adenocarcinoma is one of the most aggressive and rapidly fatal types of malignant lung tumor. Molecular docking and virtual screening were effectively and systematically used to identify specific targets in malignant tumors and screen potential drugs. Here, we screen perfect leading compounds from a medicate library (ZINC15 database) and analyze their properties (conveyance, absorption, metabolism,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36847041
DOI: 10.1097/CAD.0000000000001428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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