Back to search

Article

hsa-miR-181-5p inhibits human immunodeficiency virus type 1 replication by downregulating DDX3X expression

2022-03-29

Abstract excerpt

<title>Abstract</title> <p>The adverse effects of antiviral therapy have prompted research into novel treatment strategies. miR-181 has been shown to be negatively correlated with the HIV viral load. We predicted that miR-181 could target DDX3X, a host factor involved in HIV nuclear export leading to the inhibiting of HIV replication. To verify our hypothesis, an miR-181 mimic was transfected into Jurkat cells in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a0e14d0f-06f5-5bd2-b4aa-501d6a3a8cfb
DOI
10.21203/rs.3.rs-1487964/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
hsa-miR-181-5p inhibits human immunodeficiency virus type 1 replication by downregulating DDX3X expressionDOI 10.21203/rs.3.rs-1487964/v1
Role of long noncoding RNA in regulating HIV infection—a comprehensive reviewSemantic proximity
The sequestration of miR-642a-3p by a complex formed by HIV-1 Gag and human Dicer increases AFF4 expression and viral productionSemantic proximity
MicroRNA profiling in plasma of HIV-1 infected patients: potential markers of infection and immune statusSemantic proximity
HIV-1-encoded antisense RNA suppresses viral replication for a prolonged period.Semantic proximity
Restored lncRNAs After ART Therapy Have Potential Key Roles in the Recovery From AIDSSemantic proximity
Expression profiling of human milk derived exosomal microRNAs and their targets in HIV-1 infected mothersSemantic proximity
MiR-217 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation by down-regulation of SIRT1Semantic proximity
MicroRNA 181 Suppresses Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection by Targeting PRRSV Receptor CD163Semantic proximity
Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivationSemantic proximity
Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis.Semantic proximity
miR-223 inhibits dengue virus replication by negatively regulating the microtubule-destabilizing protein STMN1 in EAhy926 cellsSemantic proximity
Altered pattern of circulating miRNAs in HIV lipodystrophy perturbs key adipose differentiation and inflammation pathwaysSemantic proximity
Select a neighboring publication to make it the new centre.