Measuring the Contribution of Genomic Predictors to Improving Estimator Precision in Randomized trials

Abstract excerpt

The use of genomic data in the clinic has not been as widespread as was envisioned when sequencing and genomic analysis became common techniques. An underlying difficulty is the direct assessment of how much additional information genomic data are providing beyond standard clinical measurements. This is hard to quantify in the clinical setting where laboratory tests based on genomic signatures are fairly new and t...

Topics

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• Area Under Curve
• Breast Neoplasms
• Decision Making
• Genetic Predisposition to Disease
• Genetic Testing
• Mammography
• Polymorphism, Single Nucleotide
• Precision Medicine

Identifiers and source

Literature Corpus work

a0d35b07-5a14-5acd-ba1b-b61bfae5ffbf

DOI

10.1101/018168