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Article

Potential impact of genetic testing on cancer prevention trials, using breast cancer as an example.

Journal of the National Cancer Institute - 2 Aug 1995

Baker S G, Freedman L S

Abstract excerpt

Using breast cancer as an example, we explored the potential impact that a highly predictive genetic test could have on the design and analysis of cancer prevention trials. We discuss three situations in this article: 1) trials that are in progress when the genetic test first becomes available as a research tool but is not available for general use, 2) trials in progress when the genetic test becomes generally...

Topics

Adult
Age Factors
Breast Neoplasms
Clinical Trials as Topic
Female
Genetic Carrier Screening
Genetic Testing
Humans
Middle Aged
Mutation
Research Design
Risk

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7674318
DOI: 10.1093/jnci/87.15.1137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7674318-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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