Article
Phylogenetic diversity of Mycobacterium tuberculosis in two geographically distinct locations in Botswana - The Kopanyo Study.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2020
Click Eleanor S, Finlay Alyssa, Oeltmann John E, Basotli Joyce, Modongo Chawangwa, Boyd Rosanna, Wen Xiao Jun, Shepherd James, Moonan Patrick K, Zetola Nicola M
Abstract excerpt
Mycobacterium tuberculosis complex (MTBC) is divided into several major phylogenetic lineages, with differential distribution globally. Using population-based data collected over a three year period, we performed 24-locus Mycobacterial Interspersed Repeat Unit - Variable Number Tandem Repeat (MIRU-VNTR) genotyping on all culture isolates from two districts of the country that differ in tuberculosis (TB) incidence...
Topics
- Bacterial Typing Techniques
- Botswana
- Cluster Analysis
- Genetic Variation
- Genotype
- Humans
- Interspersed Repetitive Sequences
- Molecular Epidemiology
- Mycobacterium tuberculosis