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Hesperetin inhibits foam cell formation in macrophages via activating LXRα signal in an AMPK dependent manner

2020-01-23

Abstract excerpt

Cholesterol efflux from macrophages is the first step of cholesterol reverse transport (RCT), whose increase inhibits cholesterol accumulation and foam cell formation to suppress atherogenesis. Liver X receptor alpha (LXRα) and adenosine monophosphate activated protein kinases (AMPK) both have the pivotal role in cholesterol homeostasis. However the association between these two molecules in cell model of atherosc...

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Literature Corpus work
a05170b1-7e39-5722-aadf-2a362a534c68
DOI
10.1101/2020.01.22.915819
Open publication

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Hesperetin inhibits foam cell formation in macrophages via activating LXRα signal in an AMPK dependent mannerDOI 10.1101/2020.01.22.915819
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