Article

An optimized low-dose STZ model rapidly induces diabetic neuropathy in rats

2025-10-02

Abstract excerpt

<h4>Background</h4> Diabetic neuropathy is one of the most common complications of diabetes mellitus and remains difficult to study due to the prolonged experimental periods and high mortality frequently associated with conventional streptozotocin (STZ)-induced models. We aimed to develop and characterize a rapid, reproducible, and high-survival rat model of early diabetic neuropathy and to identify molecular alt...

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Literature Corpus work: 757f1317-01e6-5032-9fc2-cf7d733944c2
DOI: 10.1101/2025.10.02.679000

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