Article

The Enteric Nervous System is Essential for Functional Muscle Layer Formation in Small Bowel Bioengineering

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Tissue engineering is emerging as a promising treatment for patients with Short Bowel Syndrome (SBS). However, an important challenge is to reach a functional muscle in vitro, which would be essential to ensure intestinal motility.In this study, we investigated the co-culture of rat Smooth Muscle Cells (SMCs) and Enteric Nervous System (ENS) cells in layered 3D collagen-based scaffolds....

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Literature Corpus work: a01dc010-ffd0-5f24-8503-1ef2994729fa
DOI: 10.21203/rs.3.rs-6735240/v1

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