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Multiomics data analysis identifies TM4SF4 as a cell surface target in hepatocellular carcinoma

2024-07-03

Abstract excerpt

<h4>ABSTRACT</h4> The clinical application of cellular immunotherapy in hepatocellular carcinoma (HCC) is impeded by the lack of a cell surface target frequently expressed in HCC cells and with minimal presence in normal tissues to reduce on-target, off-tumor toxicity. In this in silico analysis, a longlist of genes (n=12,948) expressed in HCCs according to The Human Protein Atlas database were examined. The aim...

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Literature Corpus work
9fdc2816-29a1-515a-9a1c-041d49737ced
DOI
10.1101/2024.07.01.601537
Open publication

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Multiomics data analysis identifies TM4SF4 as a cell surface target in hepatocellular carcinomaDOI 10.1101/2024.07.01.601537
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