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Article

Tumor suppressor gene mutations correlate with prognosis and immunotherapy benefit in hepatocellular carcinoma.

International immunopharmacology - 1 Dec 2021

Liu Zaoqu, Liu Long, Guo ChunGuang, Yu Sun, Meng Lingfang, Zhou Xueliang, Han Xinwei

Abstract excerpt

INTRODUCTION: The tumor microenvironment (TME) has profound impacts on prognosis and immunotherapy. The TME can be altered by the genomic mutations on specific tumor-suppressor genes (TSG), thus, comprehending the association between TME and TSG in hepatocellular carcinoma (HCC) is imperative. METHODS: With a total of 1699 HCC patients from 6 international multicenter cohorts, we delineated the mutational...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34789428
DOI: 10.1016/j.intimp.2021.108340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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