Article
Evolving gene therapy approaches for osteosarcoma using viral vectors: review.
Bone - 1 Apr 2007
Witlox M A, Lamfers M L, Wuisman P I J M, Curiel D T, Siegal G P
Abstract excerpt
This review begins with an introduction to the malignant bone tumor, osteosarcoma [OS] and then moves to a discussion of the commonly used vectors for gene transfer. We first briefly highlight non-viral vectors including polymeric and liposomal delivery systems but concentrate predominantly on the 5 leading viral vectors used in cancer gene therapy, specifically retroviruses, adeno-associated viruses, herpes...
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