Article

Time-dependent Mitochondrial Remodeling in Experimental Atrial Fibrillation and Potential Therapeutic Relevance

2025-02-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Changes in mitochondria have been implicated in atrial fibrillation (AF), but their manifestations and significance are poorly understood. Here, we studied changes in mitochondrial morphology and function during AF and assessed the effect of a mitochondrial-targeted intervention in a large animal model. <h4>METHODS AND RESULTS</h4> Atrial cardiomyocytes (ACMs) were isolated...

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Literature Corpus work: 9fa4aa21-8595-58fe-98c2-64a0ca306a80
DOI: 10.1101/2025.01.29.635508

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