Oxidative Stress, Mitochondrial Homeostasis, and Sirtuins in Atrial Fibrillation

Abstract excerpt

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Yet, its treatment has serious challenges and is unsuccessful in a considerable fraction of pa-tients. One reason may be a limited understanding of the molecular mechanisms un-derlying AF. Recent studies suggest that oxidative stress is involved in AF pathogenesis. Enhanced oxidative stress is largely determined by disrupted mitochondrial homeo-stasis...

Topics

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• Action Potentials
• Atrial Fibrillation
• Comorbidity
• Heart Conduction System
• Heart Rate
• Life Style
• Mitochondrial Function and Pathology
• Racial Groups

Identifiers and source

Literature Corpus work

d4dbd673-96ef-589b-abe9-6f7ea4e12db0

DOI

10.20944/preprints202511.1773.v1