Article

Population-Scale Sequencing Data Enables Precise Estimates of Y-STR Mutation Rates

2016-01-15

Abstract excerpt

Short Tandem Repeats (STRs) are mutation-prone loci that span nearly 1% of the human genome. Previous studies have estimated the mutation rates of highly polymorphic STRs using capillary electrophoresis and pedigree-based designs. While this work has provided insights into the mutational dynamics of highly mutable STRs, the mutation rates of most others remain unknown. Here, we harnessed whole-genome sequencing da...

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Literature Corpus work: 9f91bff4-b71e-5f49-8459-cc89b47df525
DOI: 10.1101/036590

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